Explore comprehensive mapping of double-stranded RNA structures across the human genome. Our analysis using dsRNAscan identified over 5 million putative dsRNAs, providing insights into their structure, thermodynamics, and genomic distribution.

The human transcriptome contains millions of A-to-I editing sites arising from an unclear number of poorly characterized dsRNAs. Our comprehensive analysis provides new insights into RNA structure and function.

Key Findings:

• 5+ million dsRNAs predicted across the genome
• Machine learning validation using chemical probing data
• Neuronal enrichment of dsRNA structures
• Intermolecular interactions between RNA molecules
• Conservation patterns across vertebrate evolution